Publicaties

Publicaties 2023 

Steenhuis M, Wouters E, Schrezenmeier H, Rispens T, Tiberghien P, Harvala H, Feys HB, van der Schoot CE; SUPPORT-E Collaborators. Quality assessment and harmonization of laboratories across Europe for multiple SARS-CoV-2 serology assays. Vox Sang. 2023 Jul 4. doi: 10.1111/vox.13480. Epub ahead of print. PMID: 37401414.

Wouters E, Verbrugghe C, Abdelnabi R, Devloo R, De Clippel D, Jochmans D, De Bleser D, Weynand B, Compernolle V, Neyts J, Feys HB. Intranasal administration of convalescent plasma protects against SARS-CoV-2 infection in hamsters. EBioMedicine. 2023 Jun;92:104597. doi: 10.1016/j.ebiom.2023.104597. Epub 2023 May 4. PMID: 37148586; PMCID: PMC10171892.

Six KR, Debaene C, Van den Hauwe M, De Rycke R, Gardiner EE, Compernolle V, Feys HB. GPIbα shedding in platelets is controlled by strict intracellular containment of both enzyme and substrate. J Thromb Haemost. 2023 Mar 29:S1538-7836(23)00251-9. doi: 10.1016/j.jtha.2023.03.020. Epub ahead of print. PMID: 37001816.

Delabie W, De Bleser D, Vandewalle V, Vandekerckhove P, Compernolle V, Feys HB. Single step method for high yield human platelet lysate production. Transfusion. 2023 Feb;63(2):373-383

Publicaties 2022

Deconinck SJ, Nix C, Barth S, Bennek-Schöpping E, Rauch A, Schelpe AS, Roose E, Feys HB, Pareyn I, Vandenbulcke A, Muia J, Vandenbriele C, Susen S, Meyns B, Tersteeg C, Jacobs S, De Meyer SF, Vanhoorelbeke K. ADAMTS13 inhibition to treat acquired von Willebrand syndrome during mechanical circulatory support device implantation. J Thromb Haemost. 2022 Dec;20(12):2797-2809

Delaney M, Andrews J, Virk M, Barber JR, Bost JE, Baech J, Feys HB. Multinational Analysis of Children Transfused With Pathogen Inactivated Platelets. Hosp Pediatr. 2022 Mar 1;12(3):311-316

Publicaties 2021

Wouters E, Verbrugghe C, Devloo R, Debruyne I, De Clippel D, Van Heddegem L, Van Asch K, Van Gaver V, Vanbrabant M, Muylaert A, Compernolle V, Feys HB. “A novel competition ELISA for the rapid quantification of SARS-CoV-2 neutralizing antibodies in convalescent plasma.” Transfusion. 2021 Oct;61(10):2981-2990

Dekimpe C, Roose E, Kangro K, Bonnez Q, Vandenbulcke A, Tellier E, Kaplanski G, Feys HB, Tersteeg C, Männik A, De Meyer SF, Vanhoorelbeke K. “Determination of anti-ADAMTS-13 autoantibody titers in ELISA: Influence of ADAMTS-13 presentation and autoantibody detection.” J Thromb Haemost. 2021 Sep;19(9):2248-2255

Nguyen D, Simmonds P, Steenhuis M, Wouters E, Desmecht D, Garigliany M, Romano M, Barbezange C, Maes P, Van Holm B, Mendoza J, Oyonarte S, Fomsgaard A, Lassaunière R, Zusinaite E, Resman Rus K, Avšič-Županc T, Reimerink JH, Brouwer F, Hoogerwerf M, Reusken CB, Grodeland G, Le Cam S, Gallian P, Amroun A, Brisbarre N, Martinaud C, Leparc Goffart I, Schrezenmeier H, Feys HB, van der Schoot CE, Harvala H. “SARS-CoV-2 neutralising antibody testing in Europe: towards harmonisation of neutralising antibody titres for better use of convalescent plasma and comparability of trial data.” Euro Surveill. 2021 Jul;26(27):2100568

Jacquot C, Feys HB. “The need for and challenges of comparing SARS-CoV-2 antibody assays.” Transfus Med. 2021 Jun;31(3):147-148

Wouters E, Steenhuis M, Schrezenmeier H, Tiberghien P, Harvala H, Feys HB, van der Schoot E. “Evaluation of SARS-CoV-2 antibody titers and potency for convalescent plasma donation: a brief commentary” Vox Sang. 2021 May;116(5):493-496

Velásquez Pereira LC, Roose E, Graça NAG, Sinkovits G, Kangro K, Joly BS, Tellier E, Kaplanski G, Falter T, Von Auer C, Rossmann H, Feys HB, Reti M, Prohászka Z, Lämmle B, Voorberg J, Coppo P, Veyradier A, De Meyer SF, Männik A, Vanhoorelbeke K. “Immunogenic hotspots in the spacer domain of ADAMTS13 in immune-mediated thrombotic thrombocytopenic purpura.” J Thromb Haemost. 2021 Feb;19(2):478-488

Breukers J, Horta S, Struyfs C, Spasic D, Feys HB, Geukens N, Thevissen K, Cammue BPA, Vanhoorelbeke K, Lammertyn J. “Tuning the Surface Interactions between Single Cells and an OSTE+ Microwell Array for Enhanced Single Cell Manipulation” ACS Appl. Mater. Interfaces 2021 Jan 20;13(2):2316-2326

Publicaties 2020

Jacquot C, Feys HB “The need for and challenges of comparing SARS-CoV-2 antibody assays” Transf Med 2020 in press

Wouters E, Steenhuis M, Schrezenmeier H, Tiberghien P, Harvala H, Feys HB, van der Schoot E. “Evaluation of SARS-CoV-2 antibody titers and potency for convalescent plasma donation: a brief commentary” Vox Sanguinis 2020 Dec 23

Velásquez Pereira LC, Roose E, Graça NAG, Sinkovits G, Kangro K, Joly BS, Tellier E, Kaplanski G, Falter T, Von Auer C, Rossmann H, Feys HB, Reti M, Prohászka Z, Lämmle B, Voorberg J, Coppo P, Veyradier A, De Meyer SF, Männik A, Vanhoorelbeke K. “Immunogenic hotspots in the spacer domain of ADAMTS13 in immune-mediated thrombotic thrombocytopenic purpura” Journal of Thrombosis and Haemostasis 2020 Nov 10

Roose E, Schelpe AS, Tellier E, Sinkovits G, Joly BS, Dekimpe C, Kaplanski G, Le Besnerais M, Mancini I, Falter T, Von Auer C, Feys HB, Reti M, Rossmann H, Vandenbulcke A, Pareyn I, Voorberg J, Greinacher A, Benhamou Y, Deckmyn H, Fijnheer R, Prohászka Z, Peyvandi F, Lämmle B, Coppo P, De Meyer SF, Veyradier A, Vanhoorelbeke K “Open ADAMTS13, induced by antibodies, is a biomarker for subclinical immune-mediated thrombotic thrombocytopenic purpura” Blood 2020 Jul 16;136(3):353-361

Six KR, Compernolle V, Feys HB “Platelet Biochemistry and Morphology after Cryopreservation” International Journal of Molecular Sciences 2020 Jan;21(3):935

Dekimpe C, Roose E, Tersteeg C, Joly BS, Dewaele A, Horta S, Pareyn I, Vandenbulcke A, Deckmyn H, Feys HB, Tellier E, Kaplanski G, Scully M, Coppo P, De Meyer SF, Veyradier A, Vanhoorelbeke K “Anti-ADAMTS13 autoantibodies in immune-mediated thrombotic thrombocytopenic purpura do not hamper ELISA-based quantification of ADAMTS13 antigen” Journal of Thrombosis and Haemostasis 2020 Jan; [Epub ahead of print]

Delabie W, Maes W, Devloo R, Van den Hauwe MR, Vanhoorelbeke K, Compernolle V, Feys HB “The senotherapeutic nicotinamide riboside raises platelet nicotinamide adenine dinucleotide levels but cannot prevent storage lesion” Transfusion 2020 Jan;60(1):165-174

Publicaties 2019:

Six KR, Lyssens S, Devloo R, Compernolle V, Feys HB “The ice recrystallization inhibitor polyvinyl alcohol does not improve platelet cryopreservation” Transfusion 2019 Sep;59(9):3029-3031

Six KR, Devloo R, Compernolle V, Feys HB “Impact of cold storage on platelets treated with Intercept pathogen inactivation” Transfusion 2019 Aug;59(8):2662-2671

Six KR, Sicot G, Devloo R, Feys HB, Baruch D, Compernolle V “A comparison of haematopoietic stem cells from umbilical cord blood and peripheral blood for platelet production in a microfluidic device” Vox Sanguinis 2019 May;114(4):330-339

Feys HB, Van Aelst B, Compernolle V “Biomolecular Consequences of Platelet Pathogen Inactivation Methods” Transfusion Medicine Reviews 2019 Jan;33(1):29-34

2018

Six KR, Delabie W, Devreese KMJ, Johnson L, Marks DC, Dumont LJ, Compernolle V, Feys HB “Comparison between manufacturing sites shows differential adhesion, activation, and GPIbα expression of cryopreserved platelets” Transfusion 2018 Nov;58(11):2645-2656

Palyu E, Harsfalvi J, Tornai T, Papp M, Udvardy M, Szekeres-Csiki K, Pataki L, Vanhoorelbeke K, Feys HB, Deckmyn H, Tornai I “Major Changes of von Willebrand Factor Multimer Distribution in Cirrhotic Patients with Stable Disease or Acute Decompensation” Thrombosis and Haemostasis 2018 Aug;118(8):1397-1408

Feys HB, Devloo R, Sabot B, Coene J and Compernolle V “Comparison of three commercially available buffy coat pooling sets for the preparation of platelet concentrates” Vox Sanguinis 2018 May 24;113:555-561

Six KR, Devloo R, Van Aelst B, Vandekerckhove P, Feys HB and Compernolle V “A Microfluidic Flow Chamber Model for Platelet Transfusion and Hemostasis Measures Platelet Deposition and Fibrin Formation in Real-time” Journal of Visualized Experiments 2017 Feb 14;(120)

2017

Feys HB, Devloo R, Sabot B, De Pourcq K, Coene J and Compernolle V “High platelet content can increase storage lesion rates following Intercept pathogen inactivation primarily in platelet concentrates prepared by apheresis” Vox Sanguinis 2017 Sep 27; Nov;112(8):751-758

Six KR, Devloo R, Van Aelst B, Vandekerckhove P, Feys HB and Compernolle V “A Microfluidic Flow Chamber Model for Platelet Transfusion and Hemostasis Measures Platelet Deposition and Fibrin Formation in Real-time” Journal of Visualized Experiments 2017 Feb 14;(120)

2016

Van Aelst B, Devloo R, Zachée P, t'Kindt R, Sandra K, Vandekerckhove P, Compernolle V and Feys HB “Psoralen and Ultraviolet A Light Treatment Directly Affects Phosphatidylinositol 3-Kinase Signal Transduction by Altering Plasma Membrane Packing” Journal of Biological Chemistry 2016 Nov 18;291(47):24364-24376

Feys HB, Pottel H, Coene J, Vandewalle G, Vandekerckhove P and Compernolle V “Persistent aggregates in apheresis platelet concentrates are commonly collected from donors with a history of aggregate donation” Vox Sanguinis 2016 Nov;111(4):431-433

Feys HB, Van Aelst B, Devloo R, Vandekerckhove P and Compernolle V “The contribution of von Willebrand factor-GPIbα interactions to persistent aggregate formation in apheresis platelet concentrates” Vox Sanguinis 2016 May 110(4):344-51

Van Aelst B, Feys HB, Devloo R, Vandekerckhove P and Compernolle V “Microfluidic flow chambers using reconstituted blood to model hemostasis and platelet transfusion, in vitro” Journal of Visualized Experiments 2016 Mar 19;(109)

Van Aelst B, Feys HB, Devloo R, Vandekerckhove P and Compernolle V “Microfluidic flow chambers using reconstituted blood to model hemostasis and platelet transfusion, in vitro” Journal of Visualized Experiments 2016 in press (.pdf)

 2015

Van der meer PF, Dumont LJ, Lozano M, Bondar N, Wong J, Ismay S, Pink J, Nussbaumer W, Coene J, Feys HB, Compernolle V, et al “International Forum: Aggregates in platelet concentrates” Vox Sanguinis 2015 Jan 108(1):96-10. (.pdf)

Feys HB, Coene J, Devloo R, Van Aelst B, Pottel H, Vandekerckhove P and Compernolle V “Persistent aggregates in apheresis platelet concentrates” Vox Sanguinis 2015 May;108(4):367-77 (.pdf)

Drawz SM, Marschner S, Yañez M, García de Coca A, Feys HB, Deeren D and Coene J “Observational study of corrected count increments after transfusion of platelets treated with riboflavin pathogen reduction technology in additive solutions” Transfusion 2015 Jul;55(7):1745-51 (.pdf)

Van Aelst B, Devloo R, Vandekerckhove P, Compernolle V and Feys HB “Ultraviolet C light pathogen inactivation treatment of platelet concentrates preserves integrin activation but affects thrombus formation kinetics on collagen in vitro” Transfusion 2015 Oct;55(10):2404-14 (.pdf)

Van Aelst B, Feys HB, Devloo R, Vanhoorelbeke K, Vandekerckhove P and Compernolle V “Riboflavin and amotosalen photochemical treatments of platelet concentrates reduce thrombus formation kinetics in vitro” Vox Sanguinis 2015 May;108(4):328-39 (.pdf)

Deforche L, Roose E, Vandenbulcke A, Vandeputte N, Feys HB, Springer TA, Mi LZ, Muia J, Sadler JE, Soejima K, Rottensteiner H, Deckmyn H, De Meyer SF, Vanhoorelbeke K “Linker regions and flexibility around the metalloprotease domain account for conformational activation of ADAMTS-13” J Thromb Haemost 2015 Nov;13(11):2063-75 (.pdf)

Feys HB, Van Aelst B, Devloo R, Vandekerckhove P and Compernolle V “The contribution of von Willebrand factor-GPIbα interactions to persistent aggregate formation in apheresis platelet concentrates” Vox Sanguinis 2015 in press (.pdf)

 

2014

Coene J, Devreese K, Sabot B, Feys HB, Compernolle V and Vandekerckhove Ph “Paired Analysis of Plasma Proteins and Coagulant Capacity Following Treatment with Three Methods of Pathogen Reduction” Transfusion 2014 May;54(5):1321-31 (.pdf)

Deckmyn H and Feys HB “Assays for quality control of platelets for transfusion” ISBT Science Series (2013) 8, 221-4 (.pdf)

Feys HB, Van Aelst B, Devreese K, Devloo R, Coene J, Vandekerckhove Ph and Compernolle V “Oxygen removal during pathogen reduction preserves protein function in plasma for transfusion” Vox Sanguinis 2014 May;106(4):307-15 (.pdf)

De Clippel D, Baeten M, Torfs A, Emonds MP, Feys HB, Compernolle V and Vandekerckhove Ph “Screening for HLA antibodies in plateletpheresis donors with a history of transfusion or pregnancy” Transfusion 2014 Dec;54(12):3036-42 (.pdf)

Muia J, Zhu J, Gupta G, Haberichter SL, Friedman KD, Feys HB, Deforche L, Vanhoorelbeke K, Westfield LA, Roth R, Tolia NH, Heuser JE and Sadler JE “Allosteric activation of ADAMTS13 by von Willebrand factor” Proceeding of the National Academy of Sciences of the United States of America 2014 Dec;111(52):18584-9 (.pdf)

2013

Feys HB, Vandekerckhove Ph and Compernolle V “Nitric oxide levels increase during platelet concentrate production from buffy coats, but not during storage” Transfusion 2013 Jan;53(1):233-234 (.pdf)